Centrifugation Solutions
for Bioprocessing

Centrifugation Solutions
for Bioprocessing

Optimizing Centrifugation

Centrifugation requires low-shear, low-pulsation and constant-flow biologic product transfer. CPC Biotech offers best-in-class pumps, flow sensors, meters and flow controls engineered to reliably and safely transfer and precisely meter critical biologic liquids handled during depth filtration. Our advanced technology ensures optimal performance in depth filtration systems, which are essential for the purification and processing of biopharmaceutical products.

Importance of Centrifugation in the Biopharma Industry

Centrifugation is a critical process in the biopharmaceutical industry, used for separating and purifying cells, proteins, nucleic acids and other biological materials. By applying centrifugal force, this technique separates components based on their size, shape and density, making it a key step in the purification of vaccines, monoclonal antibodies and therapeutic proteins. Given the complexity and sensitivity of biologic products, centrifugal processes must be conducted with precision and care to maintain product integrity and ensure patient safety.

CPC Biotech solutions optimize centrifugation workflows with precise flow control, non-invasive monitoring, and aseptic connections, ensuring consistent separation, maximal recovery, and minimal product loss in both batch and continuous processes.

Engineered for single-use systems and sterile operations, these tools address challenges like increased debris, contamination risks, and frequent changeovers in multi-product facilities. By delivering low-shear transfers, accurate metering, and quick, contamination-free integrations, we reduce process time, validation burdens, and operational costs—enabling biomanufacturers to achieve superior yields, regulatory compliance, and faster time-to-market.

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Key Benefits of Centrifugation Solutions

  • Enhanced Recovery and Purity: Gentle handling and stable flow prevent denaturation and inconsistent separation, maximizing cell viability and product integrity.
  • Minimized Contamination Risk: Closed, aseptic systems eliminate microbial ingress during media transfers, supporting high-density cultures without cross-contamination.
  • Operational Efficiency: Quick changeovers and optimized flow rates shorten production runs, reduce cleaning needs, and accommodate diverse feed streams.
  • Cost Reduction: Single-use components lower capital investment, validation efforts, and equipment footprints for scalable, flexible operations.
  • Precision Monitoring: Real-time, non-invasive measurements ensure constant flow and pressure control, enhancing centrifugation performance.
  • Regulatory Compliance: USP Class VI materials, gamma-sterilizable designs, and rigorous testing (including torture-to-failure) provide extractables reports and sterility assurance.

Our Products

Connectors
Pumps
Flow Meters & Sensors

Connectors

CPC Biotech provides a wide range of industry leading single-use connection technologies to ensure confidence at every point of connection in critical biopharma applications, regardless of size, configuration or complexity.
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Pumps

CPC Biotech provides a wide range of best-in-class pump technologies to ensure low shear fluid handling for optimal yields, easy operation and scalable solutions from laboratory micro dosing to large volume manufacturing.
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Flow Meters & Sensors

CPC Biotech offers a variety of flow meter and sensor technologies to deliver superior accuracy and reliability for delicate fluid measurement in upstream and downstream bioprocessing applications.
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