In the final stages of biopharmaceutical manufacturing, bulk fill—often part of the broader fill-and-finish process—is essential for transferring and precisely metering critical biologic liquids into vials, syringes, ampoules, or other single-use containers, ensuring the efficacy, safety, and sterility of the final product. This stage handles shear-sensitive biologics like monoclonal antibodies, vaccines, therapeutic proteins, and active pharmaceutical ingredients (APIs), where even minor deviations in flow can impact potency, uniformity, and regulatory compliance.
Our solutions deliver stable, low-pulsation flow rates, low-shear transfers, and contamination-free aseptic connections, optimizing single-use systems for batch and continuous operations while minimizing risks like overfill, underfill, and spallation (particle shedding that compromises purity).
Our solutions deliver stable, low-pulsation flow rates, low-shear transfers, and contamination-free aseptic connections, optimizing single-use systems for batch and continuous operations while minimizing risks like overfill, underfill, and spallation (particle shedding that compromises purity).
Engineered for sterile environments, these tools integrate seamlessly with fill-and-finish systems, process containers, tubing manifolds, and equipment—reducing validation burdens, cleaning needs, and storage requirements. By providing accurate metering, gentle handling, and quick changeovers, we enable biomanufacturers to achieve consistent dosing, higher yields, and faster time-to-market, all while upholding patient safety and process reliability.
Integrated Solution: Combine AseptiQuik with Quattroflow pumps and SumoFlo sensors for a fully aseptic bulk fill loop—precisely metering and transferring liquids with zero spallation or contamination risk.
Our products integrate for end-to-end fill-and-finish support:
All components undergo rigorous testing for reproducible performance and supply assurance. Enhance your fill-and-finish for maximum efficiency, purity, and compliance.
Maintain integrity of your closed system fluid transfers with sterile connection technologies.
Maintain integrity of your closed system fluid transfers with sterile disconnect technologies.
All-in-one combination sterile connection and disconnection products.
Create a sterile link between pre-sterilized systems and stainless process equipment.
Fluid transfer quick and easy with open-format quick connectors.
The leading, self-priming, low shear pump for optimum bioprocessing yields and easy operation.
Contactless lobe pump technology providing elimination of abrasion and product contamination.
Precision flow measurement no matter the fluid type or temperature.
Scalable, easy-to-use flow meters with reusable transmitter and single-use sensor.
Pre-calibrated flow meters with non-invasive sensor preventing additional shear stress.